Validation of a Rapid GC-MS Method for Forensic Seized Drug Screening Applications.

ABSTRACT: With the lack of standardized validation protocols across the forensic chemistry community, validation of instrumentation can be a challenging and time-consuming task. However, this process is crucial to understanding the associated capabilities and limitations, especially for nascent technologies. Rapid GC-MS is one such emerging analytical technique being increasingly implemented in forensic laboratories due to its fast and informative screening capabilities. However, a full validation for forensic samples has yet to be published since its debut. This work presents the results of a comprehensive validation of a rapid GC-MS system for seized drug screening through the assessment of nine components: selectivity, matrix effects, precision, accuracy, range, carryover/contamination, robustnes

SUBMITTER: Capistran BA 

PROVIDER: S-EPMC11450638 | biostudies-literature | 2024 Dec

REPOSITORIES: biostudies-literature