Degree of joint risk factor control and incident chronic kidney disease among individuals with obesity.

ABSTRACT:

Aim

To investigate the extent to which joint risk factor control might attenuate the excess risk of chronic kidney disease (CKD) in participants with obesity.

Patients and methods

We included a total of 97 538 participants who were obese at baseline and matched 97 538 normal weight control participants from the UK Biobank in the analysis. The degree of joint risk factor control was assessed based on six major CKD risk factors, including blood pressure, glycated haemoglobin, low-density lipoprotein cholesterol, albuminuria, smoking and physical activity. The Cox proportional hazards models were used to estimate associations between the degree of risk factor control and risk of CKD, following participants from their baseline assessment until the occurrence of CKD, death, or th

SUBMITTER: Tang R 

PROVIDER: S-EPMC11452277 | biostudies-literature | 2024 Nov

REPOSITORIES: biostudies-literature