Patterns of intersectional tumor volumes in T2-weighted MRI and [¹⁸F]FET PET in adult glioma: a prospective, observational study.

ABSTRACT: Brain tumor volumes as assessed by magnetic resonance imaging (MRI) do not always spatially overlap with biological tumor volumes (BTV) measured by [¹⁸F]Fluoroethyltyrosine positron emission tomography ([¹⁸F]FET PET). We prospectively investigated volumetric patterns based on the extent of tumor volume overlap between the two modalities. Eighty-six patients with newly diagnosed glioma who had undergone MRI and [¹⁸F]FET PET between 2007 and 2009 were included in this prospective study and (re-)classified according to CNS WHO 2021 (Classification of Tumors of the Central Nervous System by the World Health Organization). Four different patterns of volume overlap were defined mathematically according to the extent of overlap between MRI-based T2 tumor volume (n

SUBMITTER: Weller J 

PROVIDER: S-EPMC11452397 | biostudies-literature | 2024 Oct

REPOSITORIES: biostudies-literature