Impact of truncating diffusion MRI scans on diffusional kurtosis imaging.

ABSTRACT:

Objective

Diffusional kurtosis imaging (DKI) extends diffusion tensor imaging (DTI), characterizing non-Gaussian diffusion effects but requires longer acquisition times. To ensure the robustness of DKI parameters, data acquisition ordering should be optimized allowing for scan interruptions or shortening. Three methodologies were used to examine how reduced diffusion MRI scans impact DKI histogram-metrics: 1) the electrostatic repulsion model (Opt_EEM); 2) spherical codes (Opt_SC); 3) random (Random_TRUNC).

Materials and methods

Pre-acquired diffusion multi-shell data from 14 female healthy volunteers (29±5 years) were used to generate reordered data. For each strategy, subsets containing different amounts of the full dataset were generated. The

SUBMITTER: Fouto AR 

PROVIDER: S-EPMC11452422 | biostudies-literature | 2024 Oct

REPOSITORIES: biostudies-literature