Influence of tumour grade on disease survival in male breast cancer patients: a systematic review.

ABSTRACT:

Purpose

Histological grading of tumours is a well-established biomarker used to guide treatment in female breast cancer. However, its significance in male breast cancer remains unclear. This systematic review investigates the prognostic significance of tumour grade in relation to breast cancer-specific survival (BCSS) in male breast cancer patients undergoing surgery.

Methods

MEDLINE, PUBMED Central and EMBASE databases were searched to identify randomised trials and observational studies related to male breast neoplasms, tumour grading, recurrence, and survival.

Results

A total of fifteen observational type studies were included in the review. A significant association between tumour grade and BCSS was reported in a majority of studies. This association was most evid

SUBMITTER: Kinsey-Trotman S 

PROVIDER: S-EPMC11452471 | biostudies-literature | 2024 Nov

REPOSITORIES: biostudies-literature