Enhanced oxidative stress resistance in Ustilago maydis and its implications on the virulence.

ABSTRACT: The phytopathogenic fungus Ustilago maydis causes corn smut by suppressing host plant defenses, including the oxidative burst response. While many studies have investigated how U. maydis responds to oxidative stress during infection, the consequences of heightened resistance to oxidative stress on virulence remain understudied. This study aimed to identify the effects on virulence in U. maydis strains exhibiting enhanced resistance to hydrogen peroxide (H₂O₂).To achieve this, we exposed U. maydis SG200 to 20 escalating H₂O₂ shocks, resulting in an adapted strain resistant to concentrations as high as 60 mM of H₂O₂, a lethal dose for the initial strain. Genetic analysis of the adapted strain revealed five nucleotide substitut

SUBMITTER: Cuamatzi-Flores J 

PROVIDER: S-EPMC11452521 | biostudies-literature | 2024 Oct

REPOSITORIES: biostudies-literature