Mpox Recurrence and Tecovirimat Resistance in a Patient With Advanced Human Immunodeficiency Virus Disease.

ABSTRACT: We present a case of mpox recurrence in a transgender woman with AIDS. Her recurrent lesions required several courses of antiviral therapy over a 5-month period and her monkeypox viral genome was subsequently noted to have tecovirimat resistance mutations. Interestingly, she developed a robust orthopoxvirus-specific T-cell response.

SUBMITTER: Griffith DC 

PROVIDER: S-EPMC11452800 | biostudies-literature | 2024 Oct

REPOSITORIES: biostudies-literature