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Automated Video-Based Approach for the Diagnosis of Tourette Syndrome.


ABSTRACT:

Background

The occurrence of tics is the main basis for the diagnosis of Gilles de la Tourette syndrome (GTS). Video-based tic assessments are time consuming.

Objective

The aim was to assess the potential of automated video-based tic detection for discriminating between videos of adults with GTS and healthy control (HC) participants.

Methods

The quantity and temporal structure of automatically detected tics/extra movements in videos from adults with GTS (107 videos from 42 participants) and matched HCs were used to classify videos using cross-validated logistic regression.

Results

Videos were classified with high accuracy both from the quantity of tics (balanced accuracy of 87.9%) and the number of tic clusters (90.2%). Logistic regression prediction probability provides a graded measure of diagnostic confidence. Expert review of about 25% of lower-confidence predictions could ensure an overall classification accuracy above 95%.

Conclusions

Automated video-based methods have a great potential to support quantitative assessment and clinical decision-making in tic disorders.

SUBMITTER: Schappert R 

PROVIDER: S-EPMC11452802 | biostudies-literature | 2024 Sep

REPOSITORIES: biostudies-literature

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Publications

Automated Video-Based Approach for the Diagnosis of Tourette Syndrome.

Schappert Ronja R   Verrel Julius J   Brügge Nele Sophie NS   Li Frédéric F   Paulus Theresa T   Becker Leonie L   Bäumer Tobias T   Beste Christian C   Roessner Veit V   Fudickar Sebastian S   Münchau Alexander A  

Movement disorders clinical practice 20240707 9


<h4>Background</h4>The occurrence of tics is the main basis for the diagnosis of Gilles de la Tourette syndrome (GTS). Video-based tic assessments are time consuming.<h4>Objective</h4>The aim was to assess the potential of automated video-based tic detection for discriminating between videos of adults with GTS and healthy control (HC) participants.<h4>Methods</h4>The quantity and temporal structure of automatically detected tics/extra movements in videos from adults with GTS (107 videos from 42  ...[more]

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