Molecular diversity in fusidic acid-resistant Methicillin Susceptible Staphylococcus aureus.

ABSTRACT:

Objectives

The recent emergence of fusidic acid (FA)-resistant Staphylococcus aureus has underscored the importance of active surveillance in isolating these strains. The molecular basis of fusidic acid resistance and the carriage of virulence factors in four borderline oxacillin-resistant Staphylococcus aureus (BORSA) clinical strains was assessed through phenotypical and genotypical methods.

Methods

All S. aureus clinical strains were obtained from various hospital units in Sicily. In vitro antibiotic susceptibility testing was conducted. WGS was performed using the Illumina MiSeq Platform, and data analysis was carried out to determine ST, resistome and virulome profiles.

Results

Genotypic characterization revealed that the strains belon

SUBMITTER: Bivona D 

PROVIDER: S-EPMC11452824 | biostudies-literature | 2024 Oct

REPOSITORIES: biostudies-literature