The efficacy of botulinum toxin in neuropathic pain: a systematic review.

ABSTRACT:

Introduction

Neuropathic pain (NP) is characterised as a lesion or disease directly affecting the somatosensory system. This study aims to analyse the efficacy of botulinum toxin type A (BT-A) in the treatment of neuropathic pain.

Methods

This systematic literature review, guided by PRISMA, applied the PICO strategy with the following criteria: (P = patients with neuropathic pain, I = botulinum toxin, C = placebo or active drug, and O = pain relief).

Results

Fourteen articles, all randomised controlled trials with a placebo control, were included in the review. A total of 645 patients were randomised, with 353 patients receiving treatment with botulinum toxin type A in doses ranging from 25U to 400U. The evaluated studies addressed trigeminal neuralgia, diabetic polyn

SUBMITTER: Oliveira KM 

PROVIDER: S-EPMC11452887 | biostudies-literature | 2024 Oct

REPOSITORIES: biostudies-literature