Occupational exposure to organic solvents during pregnancy and child behavior from early childhood to adolescence.

ABSTRACT:

Background

Organic solvents are used in formulating an extensive range of products for professional use. Animal and human studies suggest that in utero solvent exposure may affect neurodevelopment. Our objective was to assess the association between occupational exposure to solvents during pregnancy and child behavior aged 2-12 years.

Methods

The French mother-child cohort PELAGIE (2002-2006) included 3,421 women recruited in early pregnancy. Occupational exposure to solvents was self-reported. For 459 children, parents used a questionnaire derived from the Child Behavior Checklist and the Preschool Social Behavior Questionnaire to assess their child's behavior, at age 2, and the Strengths and Difficulties Questionnaire at ages 6 and 12. A cross-lagged structural equation mo

SUBMITTER: Tillaut H 

PROVIDER: S-EPMC11452962 | biostudies-literature | 2024 Oct

REPOSITORIES: biostudies-literature