Genome-wide association study reveals the underlying regulatory mechanisms of red blood traits in Anadara granosa.

ABSTRACT:

Background

Anadara granosa, commonly known as the blood clam, exhibits the unusual characteristic of having red blood among invertebrates. There is significant individual variation in blood color intensity among blood clams; individuals with vibrant red blood are deemed healthier and exhibit stronger stress resistance. However, the molecular basis underlying these red blood traits (RBTs) remains poorly understood.

Results

In this study, we performed genome-wide association studies (GWAS) in a population of 300 A. granosa individuals, focusing on RBTs as measured by hemoglobin concentration (HC), total hemocyte count (THC), and heme concentration (HEME). Our analysis identified 18 single nucleotide polymorphisms (SNPs) correlated with RBTs, subsequently selected 117 candidate

SUBMITTER: He X 

PROVIDER: S-EPMC11452991 | biostudies-literature | 2024 Oct

REPOSITORIES: biostudies-literature