A radiomics model for predicting perineural invasion in stage II-III colon cancer based on computer tomography.

ABSTRACT:

Background

Colon cancer, a frequently encountered malignancy, exhibits a comparatively poor survival prognosis. Perineural invasion (PNI), highly correlated with tumor progression and metastasis, is a substantial effective predictor of stage II-III colon cancer. Nonetheless, the lack of effective and facile predictive methodologies for detecting PNI prior operation in colon cancer remains a persistent challenge.

Method

Pre-operative computer tomography (CT) images and clinical data of patients diagnosed with stage II-III colon cancer between January 2015 and December 2023 were obtained from two sub-districts of Sun Yat-sen Memorial Hospital (SYSUMH). The LASSO/RF/PCA filters were used to screen radiomics features and LR/SVM models were utilized to construct radiomics model.

SUBMITTER: Guo T 

PROVIDER: S-EPMC11453003 | biostudies-literature | 2024 Oct

REPOSITORIES: biostudies-literature