Enhancing the immunomodulatory osteogenic properties of Ti-Mg alloy by Mg²⁺-containing nanostructures.

ABSTRACT: Facilitating an appropriate immune response is crucial for promoting bone tissue regeneration upon biomaterial implantation. In this study, the Mg²⁺-containing nanostructures on the surface of Ti-1.25Mg alloy were prepared by a one-step hydrothermal reaction method via regulating pH value to enhance the immunomodulatory osteogenic properties of Ti-Mg alloys. In neutral (HT7) or alkaline (HT9) hydrothermal treatment (HT) solution, the size of MgTiO₃ nanostructures formed on the surface of Ti-1.25Mg alloy is smaller than that in acidic HT solution (HT5), and lamellar Mg(OH)₂ nanostructures are found in HT7 and HT9. In addition, the sample surface has a lower roughness and higher wettability with increasing pH value. The Mg²⁺-containing nanostructur

SUBMITTER: Liang L 

PROVIDER: S-EPMC11453102 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature