^99mTc-FAPI-04 SPECT/CT outperforms contrast-enhanced CT in detecting metastasis in postoperative patients with colorectal cancer.

ABSTRACT:

Purpose

To compare the performance of ^99mTc-FAPI-04 SPECT/CT and contrast-enhanced CT (CECT) in the detection of postoperative metastasis in patients with colorectal cancer (CRC).

Methods

The postoperative patients with CRC were consecutively recruited from January 2023 to June 2023, and the enrolled patients completed ^99mTc-FAPI-04 SPECT/CT imaging and CECT examination within two weeks. Histopathological analysis and the follow-up results were used as the reference criteria. The location and number of metastatic sites and the detection accuracy between the two imaging methods were compared. The tumor-to-background ratio (TBR) of liver metastasis and lymph node metastasis in ^99mTc-FAPI-04 SPECT/CT imaging were also calculated for comparison.<

SUBMITTER: Sun D 

PROVIDER: S-EPMC11456442 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature