Uterine and Ovarian Histopathology After Testosterone for Gender Affirmation: A Systematic Review.

ABSTRACT:

Purpose

The objective of this systematic review was to evaluate the effects of testosterone on uterine and ovarian pathology in transmasculine patients at the time of gender-affirming surgery.

Methods

Searches were conducted using MEDLINE, CINAHL with Full Text, Cochrane Library, Scopus, and Europe PMC for articles published before April 5, 2021, containing concepts of testosterone use, uterine histopathology, and transgender population. The initial search yielded a total of 658 abstracts. Studies were analyzed in full text if they reported one or more uterine or ovarian histopathological findings in a noncisgender population receiving testosterone for gender affirmation. Rayyan software was used for the abstract review.

Results

This review was registered with PROSPER

SUBMITTER: Toland MK 

PROVIDER: S-EPMC11456762 | biostudies-literature | 2024 Aug

REPOSITORIES: biostudies-literature