Association between handgrip strength and small airway disease in patients with stable chronic obstructive pulmonary disease.

ABSTRACT:

Background

Chronic obstructive pulmonary disease (COPD) is associated with airflow limitation resulting from a combination of small airway disease (SAD) and parenchymal destruction. Although various diagnostic methods for SAD exist, access to these tools can be limited.

Objectives

This study aimed to explore the correlation between handgrip strength (HGS) and SAD in COPD patients.

Design

Cross-sectional prospective study.

Methods

HGS was measured using a hand dynamometer. SAD was evaluated using impulse oscillometry, with results reported as the difference between respiratory resistance at 5 and 20 Hz (R5-R20). SAD was defined as R5-R20 ⩾0.07 kPa/L/s. The receiver operator characteristic (ROC) curves, sensitivity, and specificity values were calculated to deter

SUBMITTER: Keawon T 

PROVIDER: S-EPMC11457192 | biostudies-literature | 2024 Jan-Dec

REPOSITORIES: biostudies-literature