Minimizing human interference in an online fully automated daily adaptive radiotherapy workflow for bladder cancer.

ABSTRACT:

Purpose

The aim was to study the potential for an online fully automated daily adaptive radiotherapy (RT) workflow for bladder cancer, employing a focal boost and fiducial markers. The study focused on comparing the geometric and dosimetric aspects between the simulated automated online adaptive RT (oART) workflow and the clinically performed workflow.

Methods

Seventeen patients with muscle-invasive bladder cancer were treated with daily Cone Beam CT (CBCT)-guided oART. The bladder and pelvic lymph nodes (CTV_elective) received a total dose of 40 Gy in 20 fractions and the tumor bed received an additional simultaneously integrated boost (SIB) of 15 Gy (CTV_boost). During the online sessions a CBCT was acquired and used as input for the AI-network to autom

SUBMITTER: Azzarouali S 

PROVIDER: S-EPMC11457325 | biostudies-literature | 2024 Oct

REPOSITORIES: biostudies-literature