Clinicopathological characteristics and prognosis of combined hepatocellular cholangiocarcinoma.

ABSTRACT: There is limited research on the clinicopathological characteristics of combined hepatocellular-cholangiocarcinoma (cHCC-CCA) currently. The aim of this study is to summerize the clinicopathological factors and prognosis of cHCC-CCA, which could help us understand this disease. 72 cases of cHCC-CCA from West China Hospital of Sichuan University were collected. Tissue components were reviewed by pathologists. Immunohistochemistry was used to detect the status of mismatch repair (MMR) and human epidermal growth factor receptor 2 (HER2) in cHCC-CCA, as well as the quantity and distribution of CD3⁺ T cells and CD8⁺ T cells. Fluorescence in situ hybridization was used to detect fibroblast growth factor receptor 2 (FGFR2) gene alteration. COX univariate and multivariate ana

SUBMITTER: Li Y 

PROVIDER: S-EPMC11457400 | biostudies-literature | 2024 Oct

REPOSITORIES: biostudies-literature