Mortality in patients with Dupuytren's disease in the first 5 years after diagnosis: a population-based survival analysis.

ABSTRACT: Previous studies suggest that Dupuytren's disease is associated with increased mortality, but most studies failed to account for important confounders. In this population-based cohort study, general practitioners' (GP) data were linked to Statistics Netherlands to register all-cause and disease-specific mortality. Patients with Dupuytren's disease were identified using the corresponding diagnosis code and assessing free-text fields from GP consultations. Multiple imputations were performed to estimate missing values of covariates, followed by 1:7 propensity score matching to balance cases with controls on confounding factors. A frailty proportional hazard model was used to compare mortality between both groups. Out of 209,966 individuals, 2561 patients with Dupuytren's disease were identif

SUBMITTER: van den Berge BA 

PROVIDER: S-EPMC11457468 | biostudies-literature | 2024 Oct

REPOSITORIES: biostudies-literature