Facile construction of Mo-based nanozyme system via ZIF-8 templating with enhanced catalytic efficiency and antibacterial performance.

ABSTRACT: Although Zeolitic Imidazolate Framework-8 (ZIF-8) shows significant promise in chemodynamic therapy of bacterial infections due to its large specific surface area and enzyme-like activity, it still faces a considerable gap compared to natural enzymes. The dependency on low pH and high concentrations of hydrogen peroxide ((H₂O₂) is a major factor limiting the clinical progress of nanozymes. Single-atom nanozymes (SA-zyme), which exhibit superior catalytic performance, are expected to overcome this limitation. In this study, we used ZIF-8 as a template to prepare structurally regular molybdenum-based single-atom nanozymes (Mo-zyme) by coordinating molybdenum atoms with nitrogen atoms within the zeolitic imidazolate framework and evaporating the zinc element at high temp

SUBMITTER: Jia H 

PROVIDER: S-EPMC11459012 | biostudies-literature | 2024 Sep

REPOSITORIES: biostudies-literature