Metabolomics-based biomarkers of fermented dairy and red meat intake: a randomized controlled trial in healthy adults.

ABSTRACT:

Background

Dietary assessment is usually performed through imprecise tools, leading to error-prone associations between diet and health-related outcomes. Metabolomics has been applied in recent years to develop biomarkers of food intake (BFIs) and to study metabolites in the diet-microbiome crosstalk. Candidate BFIs exist to detect intake of meat and to a lesser extent dairy, but validation and further development of BFIs are needed. Here, we aim to identify biomarkers that differentiate between intakes of red meat and dairy, to validate previously reported BFIs for these foods, and to explore the effect of protein-matched meals on selected microbial metabolites.

Methods

We conducted a randomized, controlled, cross-over single-meal study comparing a meal with highly fermente

SUBMITTER: La Barbera G 

PROVIDER: S-EPMC11459089 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature