Repetition dynamically and rapidly increases cortical, but not hippocampal, offline reactivation.

ABSTRACT: No sooner is an experience over than its neural representation begins to be transformed through memory reactivation during offline periods. The lion's share of prior research has focused on understanding offline reactivation within the hippocampus. However, it is hypothesized that consolidation processes involve offline reactivation in cortical regions as well as coordinated reactivation in the hippocampus and cortex. Using fMRI, we presented novel and repeated paired associates to participants during encoding and measured offline memory reactivation for those events during an immediate post-encoding rest period. post-encoding reactivation frequency of repeated and once-presented events did not differ in the hippocampus. However, offline reactivation in widespread cortical regions and hipp

SUBMITTER: Yu W 

PROVIDER: S-EPMC11459139 | biostudies-literature | 2024 Oct

REPOSITORIES: biostudies-literature