Ethnic-specific oral glucose tolerance (OGTT) phenotypes in women with hyperglycemia in pregnancy.

ABSTRACT:

Introduction

Ethnic differences associated with oral glucose tolerance test (OGTT) phenotypes is less studied in Southeast Asian ethnicities, especially in women with hyperglycemia in pregnancy (HIP).

Research design and methods

We retrospectively examined 3027 women at KK Women's and Children's Hospital in 2019. Of these, 508 (16.8%) women were diagnosed with HIP using the IADPSG (International Association of Diabetes and Pregnancy Study Groups) criteria at 24-28 weeks. OGTT phenotypes were classified into four mutually exclusive groups based on abnormal plasma glucose at (1) 0 hour only; (2) 1 hour only; (3) 2 hour only; (4) ≥2 timepoints (reference). Multinomial logistic regression was used to examine the association between ethnicity and OGTT phenotypes, adjusting for ma

SUBMITTER: Tan YB 

PROVIDER: S-EPMC11459354 | biostudies-literature | 2024 Oct

REPOSITORIES: biostudies-literature