Longitudinal Changes in Epigenetic Age Acceleration Across Childhood and Adolescence.

ABSTRACT:

Importance

Individuals exposed to discrimination may exhibit greater epigenetic age acceleration (ie, cellular indicators of premature aging) over time, but few studies have examined longitudinal changes in epigenetic age acceleration, the heterogeneity in these changes for diverse groups of youths, and contextual explanations (ie, discrimination) for differences by ethnicity or race.

Objective

To provide a descriptive illustration of changes in epigenetic age acceleration across childhood and adolescence among an ethnically and racially diverse sample of youths.

Design, setting, and participants

This cohort study leveraged longitudinal data on a large sample of youths from low-income households in 20 large urban US cities who provided repeated assessments of saliva t

SUBMITTER: Del Toro J 

PROVIDER: S-EPMC11459359 | biostudies-literature | 2024 Dec

REPOSITORIES: biostudies-literature