A case report of the diagnosis and treatment of immune checkpoint inhibitor-related encephalitis induced by camrelizumab.

ABSTRACT:

Background

Camrelizumab has been widely used in the treatment of various cancers, it is important to determine the side-effect of this drug and the corresponding treatment strategy.

Case description

The current case report describes the clinic, diagnosis, treatment and prognosis of camrelizumab-related encephalitis. Camrelizumab was administrated to a 67-year-old man with squamous cell carcinoma (SCC), a form of non-small cell lung cancer (NSCLC). One month after the treatment, the patient showed typical encephalitis symptoms including systemic fatigue, numbness of extremities and walking instability. Furthermore, the total protein in cerebrospinal fluid (CSF) was significantly elevated (1,399 vs. normal range 120-600 mg/L). Importantly, magnetic resonance imaging sho

SUBMITTER: Wang YY 

PROVIDER: S-EPMC11459425 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature