Navigating the archaeal frontier: insights and projections from bioinformatic pipelines.

ABSTRACT: Archaea continues to be one of the least investigated domains of life, and in recent years, the advent of metagenomics has led to the discovery of many new lineages at the phylum level. For the majority, only automatic genomic annotations can provide information regarding their metabolic potential and role in the environment. Here, genomic data from 2,978 archaeal genomes was used to perform automatic annotations using bioinformatics tools, alongside synteny analysis. These automatic classifications were done to assess how good these different tools perform in relation to archaeal data. Our study revealed that even with lowered cutoffs, several functional models do not capture the recently discovered archaeal diversity. Moreover, our investigation revealed that a significant portion of arc

SUBMITTER: Karavaeva V 

PROVIDER: S-EPMC11459464 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature