Financial toxicity in breast cancer patients receiving regional nodal irradiation: Variation by cancer subtype.

ABSTRACT:

Background

We evaluated sociodemographic and clinical predictors of financial toxicity (FT) among patients with breast cancer with higher risk clinical factors warranting regional nodal irradiation (RNI).

Methods

Among 183 participants in a clinical trial of conventional vs. hypofractionated treatment with RNI, 125 (68 %) completed a pilot survey of FT measured using the validated Economic Strain and Resilience in Cancer (ENRICh) instrument, scored from 0 (minimal) to 10 (severe) FT. Associations with predictors were evaluated using Pearson correlation coefficients and Kruskal Wallis, Mann-Whitney U, and Jonckheere-Terpstra tests. Predictors of severe FT (ENRICh≥5) were tested using multivariable logistic regression with odds ratios converted to relative risks (RR).

Resul

SUBMITTER: Smith GL 

PROVIDER: S-EPMC11459629 | biostudies-literature | 2024 Dec

REPOSITORIES: biostudies-literature