Treatment trajectories and outcomes in inflammatory bowel disease: a tertiary single-centre experience.

ABSTRACT:

Background

There is an increasing diversification in the treatment landscape for inflammatory bowel diseases (IBD) leading to therapeutic challenges that can only incompletely be covered by prospective randomized double-blind trials. Real-world observations are therefore an important tool to provide insights into therapeutic strategies.

Objectives

To describe the real-world treatment algorithms in an IBD referral centre.

Design

Single-centre retrospective cohort study.

Methods

We retrospectively analysed prospectively collected data on treatment sequences and outcomes from 502 patients with Crohn's disease (CD) and ulcerative colitis (UC) treated with infliximab, adalimumab, vedolizumab or ustekinumab at a large German tertiary referral centre.

Results

T

SUBMITTER: Wagner K 

PROVIDER: S-EPMC11459667 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature