A pilot study of the cardiopulmonary effects in healthy volunteers after exposure to high levels of PM_2.5 in a New York City subway station.

ABSTRACT:

Background

Subway systems are becoming increasingly common worldwide transporting large populations in major cities. PM_2.5 concentrations have been demonstrated to be exceptionally high when underground, however. Studies on the impact of subway PM exposure on cardiopulmonary health in the United States are limited.

Methods

Healthy volunteers in New York City were exposed to a 2-h visit on the 9th Street Station platform on the Port Authority Trans-Hudson train system. Blood pressure, heart rate variability (HRV), spirometry, and forced impulse oscillometry were measured, and urine, blood spot, and nasal swab biosamples were collected for cytokine analysis at the end of the 2-h exposure period. These endpoints were compared against individual control measurements c

SUBMITTER: Luglio DG 

PROVIDER: S-EPMC11460011 | biostudies-literature | 2024 Oct

REPOSITORIES: biostudies-literature