Associations of cardiometabolic index with diabetic statuses and insulin resistance: the mediating role of inflammation-related indicators.

ABSTRACT:

Background

This study aimed to analyze the associations of cardiometabolic index (CMI) with diabetic statuses and insulin resistance (IR) using data from the National Health and Nutrition Examination Survey (NHANES) and examined the potential mediating role of inflammation in these correlations.

Methods

This study enrolled 9477 participants across four NHANES cycles from 2011 to 2018. The primary outcomes of the study included the risk of having prediabetes, diabetes and the level of the homeostasis model assessment of IR (HOMA-IR). Other outcomes including the levels of fasting blood glucose (FBG), hemoglobin A1c (HbA1c), oral glucose tolerance test (OGTT) results, fasting insulin, the risk of oral hypoglycemic medicine use, insulin use, and retinopathy were also collected

SUBMITTER: Xu B 

PROVIDER: S-EPMC11460066 | biostudies-literature | 2024 Oct

REPOSITORIES: biostudies-literature