Biospecimens in the HEALthy Brain and Child Development (HBCD) Study: Rationale and protocol.

ABSTRACT: The HEALthy Brain and Child Development (HBCD) Study, a multi-site prospective longitudinal cohort study, will examine human brain, cognitive, behavioral, social, and emotional development beginning prenatally and planned through early childhood. The longitudinal collection of biological samples from over 7000 birthing parents and their children within the HBCD study enables research on pre- and postnatal exposures (e.g., substance use, toxicants, nutrition), and biological processes (e.g., genetics, epigenetic signatures, proteins, metabolites) on neurobehavioral developmental outcomes. The following biosamples are collected from the birthing parent: 1) blood (i.e., whole blood, serum, plasma, buffy coat, and dried blood spots) during pregnancy, 2) nail clippings during pregnancy and one

SUBMITTER: Sullivan EL 

PROVIDER: S-EPMC11460495 | biostudies-literature | 2024 Dec

REPOSITORIES: biostudies-literature