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Association of metformin use with asthma development and adverse outcomes: A systematic review and meta-analysis.


ABSTRACT:

Background

Asthma and diabetes are prevalent chronic diseases affecting a significant population globally. Research has suggested that metformin, a commonly used medication for diabetes management, may also have beneficial effects in enhancing asthma outcomes. Considering the comorbidity of asthma and diabetes, a comprehensive analysis was performed to investigate the efficacy of metformin in reducing adverse outcomes of asthma patients with diabetes.

Methods

To gather relevant data, we conducted a systematic search of the PubMed, Embase, and CENTRAL databases for observational studies published prior to September 2023. We specifically looked for studies involving individuals diagnosed with both asthma and diabetes, comparing the incidence and severity of asthma exacerbation

SUBMITTER: Rao R 

PROVIDER: S-EPMC11460891 | biostudies-literature | 2024 Oct

REPOSITORIES: biostudies-literature