[Preclinical loading in patients with acute chest pain and acute coronary syndrome - PRELOAD survey].

ABSTRACT:

Background

Guidelines on myocardial infarction (MI) recommend antithrombotic and anticoagulatory treatment at time of diagnosis. MI with ST segment elevation (STEMI) is mostly a certain diagnosis. Acute coronary syndrome without ST segment elevation (NSTE-ACS) has diagnostic uncertainty and remains a working diagnosis in the prehospital setting.

Objective

Assessment of prehospital loading with aspirin and heparin depending on ACS subtype and pretreatment with oral anticoagulants.

Methods

The PRELOAD survey was a nationwide German study. STEMI/NSTE-ACS scenarios were designed and varied in pretreatment: I) no pretreatment, II) new oral anticoagulants (NOAC), III) vitamin K antagonist (VKA). Loading strategy was assessed and included: a) aspirin (ASA), b) unfractionated

SUBMITTER: Macherey-Meyer S 

PROVIDER: S-EPMC11461559 | biostudies-literature | 2024 Oct

REPOSITORIES: biostudies-literature