Quantification of blood and CSF volume to predict outcome after aneurysmal subarachnoid hemorrhage.

ABSTRACT: This study aimed to describe the relationship between blood and CSF volumes in different compartments on baseline CT after aSAH, assess if they independently predict long-term outcome, and explore their interaction with age. CT scans from patients participating in a prospective multicenter randomized controlled trial of patients with aSAH were segmented for blood and CSF volumes. The primary outcomes were the mRS, and the Subarachnoid Hemorrhage Outcome Tool (SAHOT) at day 28 and 180. Univariate regressions were conducted to identify significant predictors of poor outcomes, followed by principal component analysis to explore correlations between imaging variables and WFNS. A multivariate predictive model was then developed and optimized using stepwise regression. CT scans from 97 patients

SUBMITTER: Booker J 

PROVIDER: S-EPMC11461592 | biostudies-literature | 2024 Oct

REPOSITORIES: biostudies-literature