The effects of dialysate calcium prescription on mortality outcomes in incident patients on hemodialysis.

ABSTRACT:

Background

The appropriate prescription of dialysate calcium concentration for hemodialysis is debated. We investigated the association between dialysate calcium and all-cause, cardiovascular mortality and sudden cardiac death.

Methods

In this historical cohort study, we included adult incident hemodialysis patients who initiated dialysis between 1 January 2010 and 30 June 2017 who survived for at least 6 months (grace period). We evaluated the association between dialysate calcium 1.25 or 1.50 mmol/l and outcomes in the 2 years after the grace period, using multivariable Cox regression models. Moreover, we examined the association between the serum dialysate to calcium gradient and outcomes.

Results

We included 12 897 patients with dialysate calcium 1.25 mmol/l and 2

SUBMITTER: Ter Meulen KJ 

PROVIDER: S-EPMC11462444 | biostudies-literature | 2024 Oct

REPOSITORIES: biostudies-literature