Association between heavy metal exposure and biomarkers for non-alcoholic fatty liver disease in Korean adolescents.

ABSTRACT:

Objectives

The global prevalence of non-alcoholic fatty liver disease (NAFLD) in adolescents has increased. In addition to childhood obesity, environmental risk factors, such as heavy metals that are known to be involved in hepatotoxicity, play role in NAFLD occurrence. However, their association with NAFLD remains unclear. This study aimed to investigate the association between heavy metal exposure and NAFLD biomarkers in adolescents.

Methods

In this cross-sectional study, we used the data of a total of 1505 adolescents aged 12-17 years who participated in the Korean National Environmental Health Survey III (2015-2017) and IV (2018-2020). The presence of blood lead (BPb), blood mercury (BHg), urinary mercury (UHg), and urinary cadmium (UCd) were measured. Liver enzymes incl

SUBMITTER: Lee DW 

PROVIDER: S-EPMC11462472 | biostudies-literature | 2024 Oct

REPOSITORIES: biostudies-literature