Prognostic impact of outpatient loop diuretic reduction patterns in patients with chronic heart failure.

ABSTRACT:

Background

The relationship between patterns of outpatient oral loop diuretic (LD) dose reduction and prognosis in patients with heart failure (HF) remains unclear.

Methods

We evaluated 679 patients with HF-prescribed LDs at baseline between September 2015 and August 2019. Dose reduction was defined as a change to a lower LD dose than the previous outpatient dose. Dose intensification was defined as a change to a higher LD dose than the previous outpatient dose. Patients were classified into no-reduction (no LD dose reduction during follow-up) and reduction groups (categorized into successive-reduction [≥2 successive LD dose reductions without intervening LD dose intensification] and single-reduction [LD dose reduction without successive dose reduction] groups). The primary

SUBMITTER: Koike T 

PROVIDER: S-EPMC11462479 | biostudies-literature | 2024 Dec

REPOSITORIES: biostudies-literature