Systematic review and Meta-analysis of brain plasticity associated with electroacupuncture in experimental ischemic stroke.

ABSTRACT:

Objective

To systematically evaluate the role of electroacupuncture in maintaining brain plasticity in ischemic stroke mediated brain damage.

Methods

We searched for all relevant trials published through Oct 7, 2022 from seven databases. Metho-dological quality was assessed using the CAMARADES Risk of Bias Tool. A Meta-analysis of comparative effects was performed using Review Manager v.5.3 software.

Results

A total of 101 studies involving 2148 animals were included. For most studies, primary outcomes results of the Meta-analysis indicate that EA significantly improved ischemic stroke rat's postsynaptic density thickness [Standardized Mean Difference (SMD) = 1.41, 95% confidence interval (CI) (0.59, 2.23), P = 0.0008], numerical density of synaps

SUBMITTER: Yingshan XU 

PROVIDER: S-EPMC11462533 | biostudies-literature | 2024 Oct

REPOSITORIES: biostudies-literature