Superior temporal sulcus folding, functional network connectivity, and autistic-like traits in a non-clinical population.

ABSTRACT:

Background

Autistic-like traits (ALT) are prevalent across the general population and might be linked to some facets of a broader autism spectrum disorder (ASD) phenotype. Recent studies suggest an association of these traits with both genetic and brain structural markers in non-autistic individuals, showing similar spatial location of findings observed in ASD and thus suggesting a potential neurobiological continuum.

Methods

In this study, we first tested an association of ALTs (assessed with the AQ questionnaire) with cortical complexity, a cortical surface marker of early neurodevelopment, and then the association with disrupted functional connectivity. We analysed structural T1-weighted and resting-state functional MRI scans in 250 psychiatrically healthy individuals wit

SUBMITTER: Nenadic I 

PROVIDER: S-EPMC11463051 | biostudies-literature | 2024 Oct

REPOSITORIES: biostudies-literature