Characterizing the soil microbial community associated with the fungal pathogen <i>Coccidioides immitis</i>.

ABSTRACT: Coccidioidomycosis is a fungal disease affecting humans and other mammals, caused by environmental pathogens of the genus Coccidioides. Understanding the ecological factors that shape the distribution of Coccidioides in soils is important for minimizing the risk of human exposure, though this remains challenging due to the pathogen's highly variable spatial distribution. Here, we examined associations between the soil microbial community and Coccidioides immitis presence within the Carrizo Plain National Monument-a minimally disturbed grassland ecosystem, and the site of a longitudinal study examining the effects of rodents and their burrows on C. immitis presence in soils. Using internal transcribed spacer 2 (ITS2) and 16S sequencing to characterize the soil fu

SUBMITTER: Radosevich M 

PROVIDER: S-EPMC11463387 | biostudies-literature | 2024 Sep

REPOSITORIES: biostudies-literature