SEISMICgraph: a web-based tool for RNA structure data visualization.

ABSTRACT: In recent years, RNA has been increasingly recognized for its essential roles in biology, functioning not only as a carrier of genetic information but also as a dynamic regulator of gene expression through its interactions with other RNAs, proteins, and itself. Advances in chemical probing techniques have significantly enhanced our ability to identify RNA secondary structures and understand their regulatory roles. These developments, alongside improvements in experimental design and data processing, have greatly increased the resolution and throughput of structural analyses. Here, we introduce SEISMICgraph, a web-based tool designed to support RNA structure research by offering data visualization and analysis capabilities for a variety of chemical probing modalities. SEISMICgraph enables s

SUBMITTER: Wightman FF 

PROVIDER: S-EPMC11463429 | biostudies-literature | 2024 Sep

REPOSITORIES: biostudies-literature