AGT, CYP11B2 & ADRB2 gene polymorphism & essential hypertension (HT): A meta-analysis.

ABSTRACT: Background & objectives The results of the genetic association studies between the selected candidate genes and hypertension (HT) contradicted across different populations. Majority of the meta-analyses carried out did not consider population genetic ancestry as a confounding factor. Therefore, this meta-analysis attempted to consolidate and re-evaluate the findings of the association between the selected candidate variants (AGT-rs699, CYP11B2-rs1799998, ADRB2-rs1042713 and rs1042714) and HT, by categorizing the genotyping data based on known genetic ancestry, and/or major geographical populations. Methods Publications were retrieved from PubMed, Cochrane and World of Science. The included articles were further divided into different populations based on their known genetic and/or geograph

SUBMITTER: Maamor NH 

PROVIDER: S-EPMC11463865 | biostudies-literature | 2024 Jun

REPOSITORIES: biostudies-literature