Hepatitis C virus genotypes among population with reported risk factors in Assam, north-east India: Emergence of genotype-8.

ABSTRACT: Background & objectives Hepatitis C virus (HCV) exhibits extensive genetic diversity in infected hosts. There are few published reports of HCV genotype (GT) distribution from the north-east Indian States lying close to the 'Golden Triangle' known for illicit drug trafficking. Real-time knowledge of HCVGT distribution is important for studies on epidemiologic aspects and virus evolution and for the development of new target-specific, direct-acting antiviral drugs. This study aims to examine the distribution of HCVGTs and their subtypes in different risk groups from Assam, north-east India. Methods It is a hospital-based cross-sectional study. Plasma samples reactive for anti-HCV antibody in enzyme-linked immunosorbent assay (ELISA) were subjected to viral load test and genotyping by real-ti

SUBMITTER: Das S 

PROVIDER: S-EPMC11463879 | biostudies-literature | 2024 Jul

REPOSITORIES: biostudies-literature