Neural mechanisms of inhibitory control in preadolescent irritability: Insights from the ABCD study.

ABSTRACT:

Objective

Elevated pediatric irritability is a transdiagnostic symptom that predicts multiple mental health problems in adolescence and adulthood. Altered top-down regulatory networks, such as inhibitory control networks that suppress an impulse in favor of goal-directed behavior, are thought to contribute to high levels of youth irritability. Nevertheless, little work has examined links between youth irritability and neural processes supporting inhibitory control in large diverse samples, nor have they focused on the key period ramping up to adolescence (i.e., preadolescence).

Method

Functional MRI data from 5380 preadolescents (age M=9.97 years, SD=0.62) in the baseline Adolescent Brain and Cognitive Development (ABCD) Study were analyzed. Parents reported on their preadol

SUBMITTER: Parker AJ 

PROVIDER: S-EPMC11464202 | biostudies-literature | 2024 Oct

REPOSITORIES: biostudies-literature