Changing human hair fibre colour and shape from the follicle.

ABSTRACT:

Introduction

Natural hair curvature and colour are genetically determined human traits, that we intentionally change by applying thermal and chemical treatments to the fibre. Presently, those cosmetic methodologies act externally and their recurrent use is quite detrimental to hair fibre quality and even to our health.

Objectives

This work represents a disruptive concept to modify natural hair colour and curvature. We aim to model the fibre phenotype as it is actively produced in the follicle through the topical delivery of specific bioactive molecules to the scalp.

Methods

Transcriptome differences between curly and straight hairs were identified by microarray. In scalp samples, the most variable transcripts were mapped by in situ hybridization. Then, by using approp

SUBMITTER: Matama T 

PROVIDER: S-EPMC11464751 | biostudies-literature | 2024 Oct

REPOSITORIES: biostudies-literature