Predictors of residential mobility and its impact on air pollution exposure among children diagnosed with early childhood leukemia.

ABSTRACT: Epidemiology studies relying on one address to assign exposures over time share common methodological limitations in failing to account for mobility that may introduce potential exposure misclassification. Using Texas birth certificate and cancer registry data, we identified predictors of residential mobility among mothers of children diagnosed with early childhood leukemia in Texas from 1995 to 2011. We used U.S. Environmental Protection Agency (EPA) National Air Toxics Assessment data to estimate residential levels of benzene and 1,3-butadiene based on addresses at birth and diagnosis and applied mixed-effects ordinal logistic regression models to evaluate differences in exposure classification between the two time periods. In total, 55% of children moved from time of birth to diagnosis,

SUBMITTER: Tee Lewis PG 

PROVIDER: S-EPMC11465071 | biostudies-literature | 2019 Jun

REPOSITORIES: biostudies-literature