Establishing a clinically applicable frailty phenotype screening tool for aging dogs.

ABSTRACT:

Introduction

Frailty is a well-defined clinical syndrome in humans caused by accumulation of impairments which result in loss of reserve capacity and increased vulnerability to disability, dependence, and death. Dogs are of particular interest in studies of frailty due to the similarities they share with people in their environment, lifestyles, and age-related diseases.

Materials and methods

The aim of this study was to develop a frailty phenotype screening tool, based on previously validated measures in dogs, which could be easily applied in the clinical setting, and which was predictive of all-cause, short term (6-month) mortality. The study was conducted in two phases. In phase 1, a retrospective cohort of 51 dogs was used to identify and evaluate potential measures for t

SUBMITTER: Russell KJ 

PROVIDER: S-EPMC11465091 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature