High-Performance Electrochemical Creatinine Sensors Based on β-Lead Dioxide/Single-Walled Carbon Nanotube Electrodes.

ABSTRACT: Creatinine is an important biomarker of kidney function and muscular metabolism. In this paper, we developed the β-lead dioxide/single-walled carbon nanotube (β-PbO₂/CNT) and the β-PbO₂/CNT ion-selective electrode (β-PbO₂/CNT/ISE), which were used as highly sensitive potentiometric sensors for creatinine detection. The fabricated electrodes exhibited highly pH-sensitive characteristics due to the synergistic effect of the electrochemical properties of CNT and β-PbO₂. Moreover, an ammonium-ion-selective membrane coating allowed the β-PbO₂/CNT electrode to be NH⁴⁺-selective for direct detection of the ammonium ion. By exploiting the electrochemical characteristics of these electrodes, the creatinine assay was established throu

SUBMITTER: Jeon SM 

PROVIDER: S-EPMC11465222 | biostudies-literature | 2024 Oct

REPOSITORIES: biostudies-literature