Proteomic Profiling in Pediococcus pentosaceus SF11 Exposed to Condensed Tannins from Sainfoin.

ABSTRACT: The antibacterial mechanism of condensed tannins (CTs) obtained from tea has been elucidated, but the mechanism of legume-derived CTs remains unclear. The mechanisms of legume- and tea-derived CTs probably differ due to the diverse compositions of CTs. Previous research found that sainfoin CTs directly inhibited the growth of Pediococcus. The present study investigated the inhibition mechanism of CTs against Pediococcus pentosaceus SF11 (SF11) through proteomic analysis. The results showed that the minimum inhibitory concentration (MIC) of CTs against SF11 was 1500 mg/L and that CTs increased cell membrane permeability in a dose-dependent manner. In total, 418 differentially expressed proteins (DEPs) were identified between the CT treatment and the control, among which 341 we

SUBMITTER: Huang R 

PROVIDER: S-EPMC11465268 | biostudies-literature | 2024 Oct

REPOSITORIES: biostudies-literature